The Sbarro Health Research Organization (SHRO) is a nonprofit charity committed to funding excellence in basic genetic research to cure and diagnose cancer, cardiovascular diseases, diabetes and other chronic illnesses and to foster the training of young doctors in a spirit of professionalism and humanism. In 1993, Antonio Giordano, M.D., Ph.D., founded the Sbarro Health Research Organization Institute with a generous donation from Mario Sbarro the Founder of the Sbarro restaurant chain, following Dr. Giordano’s discovery of the tumor suppressor gene pRb2, and cell cycle genes CDK9, CDK10. Initially named the Sbarro Institute, the research center was located at Thomas Jefferson University, where Dr. Giordano was a professor.