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Rising Cases of Respiratory Diseases in Children: An Overview of the Situation Post & News admin September 28, 2024 In recent weeks, there are concerns for a surge in respiratory diseases among children in China, prompting the World Health Organization (WHO) to intervene and investigate the nature of this outbreak. While initial reports raised the possibility of a new virus, subsequent information shared by Chinese authorities suggest a different scenario.The first alert came in late November from ProMed, the surveillance system for emerging diseases, which reported cases of “undiagnosed pneumonia” in children in China. These cases presented with high fever and lung abnormalities but lacked typical cough. Chinese health officials, in collaboration with the WHO, have then provided data on the outbreak, including laboratory results, which indicated no presence of unusual pathogens. As a result, the hypothesis of a new virus circulating in China has been largely dismissed.While some health experts, including Mandy Cohen from the Centers for Disease Control and Prevention, view the increase in respiratory diseases as relatively harmless, caution has been advised. For Instance, President Biden, has suggested limiting travel to China until further information are available.One potential explanation for the surge in respiratory illnesses among children in China likely depends on the delicate balance between human activity and the environment. This altered equilibrium could play a significant role in the development of transmissible and endemic diseases. Moreover, the prolonged restrictions imposed on children due to the Sars-Cov2 pandemic may have impacted their immune systems, potentially diminishing their ability to combat viruses.Data shared by China indicate a rise in hospitalizations of children due to influenza virus, respiratory syncytial virus, and mycoplasma pneumoniae infections, all typical pathogens for this time of year. Similar increases in mycoplasma pneumonia cases have been reported in other countries such as France and Vietnam.In Italy, two cases of mycoplasma pneumonia in children have been reported, prompting reassurance from the Institute of Health, which emphasized the fact that such infections have always been present in the community.In summary, while the situation warrants attention, current evidence suggests that the surge in respiratory diseases among children in China is primarily linked to known pathogens, and, at this time, there is no conclusive evidence of a new virus. However, monitoring and cooperation between international health organizations remain crucial to understand and effectively address this situation.Professor Antonio Giordano, M.D., Ph.D., is the creator and head of the Sbarro Health Research Organization, located at Temple University‘s College of Science and Technology in Philadelphia. Stay connected with him through his various social media platforms, including Facebook, LinkedIn, Twitter, and Instagram

Milan hosts the AmCham Transatlantic Awards with Tajani, Zappia and Markell Post & News admin September 28, 2024 Among the guests also Tracy Roberts-Pounds, Consul General of the United States in NaplesThis year, Milan hosted to the Gala Dinner of the XVII Transatlantic Award, an event organized by AmCham – the American Chamber of Commerce in Italy. AmCham is a non-profit organization that engages influential Italian and American entrepreneurs with the overarching goal of fostering economic and cultural ties between the United States and Italy. Additionally, the organization works for promoting commercial relations between members.The event saw the presence of esteemed individuals, including the Honorable Antonio Tajani, who is the Vice President of the Council and Minister of Foreign Affairs and International Cooperation. Jack Markell, the American Ambassador to Italy and San Marino, and Mariangela Zappia, the Italian Ambassador to the United States, were also among the recognized guests.Other guests included Tracy Roberts-Pounds, the Consul General of the United States in Naples, Luca Arnaboldi, the President of AmCham, Simone Crolla, the Managing Director of AmCham, Dr. Massimo Petrone from the Southern Committee of the American Chamber of Commerce, Professor Antonio Giordano, the President of the Sbarro Health Research Organization and a professor of Anatomy and Pathological Histology at the University of Siena, Dr. Antonio Giacomini, the CEO of Innovaway, cassation lawyer Giuseppe Ciliberti, and Dr. Nicolò Petrone, the CEO of 1,000 pharmacies.Professor Antonio Giordano, M.D., Ph.D., is the creator and head of the Sbarro Health Research Organization, located at Temple University‘s College of Science and Technology in Philadelphia. Stay connected with him through his various social media platforms, including Facebook, LinkedIn, Twitter, and Instagram

Medicine and Technology COMMUNICATION PROJECT CREATED BY ANTONELLA MINICHINI Smarter medicine thanks to AI and algorithms Post & News admin December 3, 2023 Professor Antonio Giordano, Director of the SHRO and Sbarro institute for Cancer Research, Temple University, a center of excellence for cancer research based in Philadelphia and founded by him in 1993 with a recently opened laboratory in Turin, Italy, says: “In oncology we will be able to make a diagnosis based on original genetic traits”.A correct use of AI in oncology could bring an advantage in the fight against cancer. For example, in the identification of certain DNA mutations, of which we know the entire sequence, explains Prof. Giordano, who is also professor of Pathological Anatomy and Histology at the University of Siena. Some genetic mutations are already present in many normal cells located near a tumor, says Giordano. An algorithm has allowed the detection of early genetic changes in benign tissues through the innovative technique of spatial transcriptomics. Ultimately, by perfecting the use of AI, we will be able to reach early diagnoses based on underlying genetic traits in a context where research achievements have positively increased the “lifespan” in the oncology field as in fact today we can simultaneously study thousands of genes and monitor their expression and related factors for designing personalized therapies for patients for precision medicine. Furthermore, non-invasive diagnostic tools have been developed for some tumors as liquid biopsies are used to monitor a pathology through a simple blood sample, analyzing the molecular characteristics of tumor cells or the circulating DNA. In this contest, research conducted at SHRO on the identification of diagnostic, prognostic and therapeutic markers can make a difference. As stated by Prof. Giordano, “new targeted therapeutic strategies can be identified by studying precise molecular alterations, for example, in mesothelioma or lung cancer, whose etiology is linked to exposure to environmental pollutants. It is no coincidence that, for years, I have been interested in the situation in Campania, better known as the Land of the fire, encouraging biomonitoring studies and requalification activities to reduce the incidence of diseases”. Factors to also monitor are impact of nutrition and new Sars-Cov2 virus strains “Studies are only apparently disconnected from each other but the common aim is to improve the quality of life in patients and reduce the occurrence of severe pathologies. Professor Antonio Giordano, M.D., Ph.D., is the creator and head of the Sbarro Health Research Organization, located at Temple University‘s College of Science and Technology in Philadelphia. Stay connected with him through his various social media platforms, including Facebook, LinkedIn, Twitter, and Instagram

Lidocaine reduces the risk of cancer relapse Post & News admin December 1, 2023 Scientific evidence supports a possible role of Lidocaine in inhibiting the activity of tumor cells. Lidocaine is not a chemotherapy drug, but a commonly used anesthetic, which appears to reduce the risk of post-operative relapses, when administered in dosages not associated with systemic toxicity.lidocaine likely inhibits proliferation and viability of tumor cells by exerting an anti-inflammatory action. Furthermore, its use in local anesthesia during breast cancer removal surgery has shown improvement in disease survival. The trial involved 1583 women recruited in 11 Indian centers, all diagnosed with surgically-removable breast cancer. It was observed that, time after treatment, patients did not present metastases.The study published in the British Journal of Anesthesia was based on previous epidemiological research, which reported a link between the anesthetic Lidocaine and a reduction in the incidence of tumor recurrence. This has opened new scenarios for its use as in fact Lidocaine is very well tolerated and has been used for years in various fields of medicine. In addition to its use in breast cancer treatment, some benefits have also been found for prostate cancer. This latest research was conducted by an Institute in Bellin zona in collaboration with the Cantonal Hospital Authority. Lidocaine blocks the transmission of chemokine receptor signals, which “guide the traffic” of cells to secondary sites, thereby effectively blocking the possibility of metastasis. Epidemiological studies attest its validity in post-operative use to relieve pain. Scientific discoveries occur when talent, intuition and observation skills come together: patients treated with lidocaine show prolonged survival and reduced relapse. As said, lidocaine is well tolerated and could constitute an effective weapon against metastases once identified the effective dosage to avoid toxicity.Professor Antonio Giordano, M.D., Ph.D., is the creator and head of the Sbarro Health Research Organization, located at Temple University‘s College of Science and Technology in Philadelphia. Stay connected with him through his various social media platforms, including Facebook, LinkedIn, Twitter, and Instagram

Legacy of Excellence: Embracing the Salerno Medical School’s Prestigious Award Post & News admin November 30, 2023 Nestled within the historical walls of the City Palace in Salerno lies a legacy that echoes through centuries—the illustrious Salerno Medical School. Each year, a cherished tradition unfolds within the Marble Hall, commemorating the School’s unparalleled influence on medical history.The Legacy of the Salerno Medical School:The Salerno Medical School stands as a beacon of enlightenment. Imagine the Middle Ages, where this institution shone brightly as the pioneer of medical education in Europe. Its teachings echoed across continents, laying the foundations for modern medical universities. During this celebration, the members designate individuals they believe deserve their award, those who at that moment best embody the goals and values of the School.“This year, with great pride, I was honored with this award during the cloak ceremony, a moving and deeply emotional moment” – Dr Antonio GiordanoCongratulations to our esteemed president for being honored with this prestigious award during the cloak ceremony this year! Such a momentous achievement that truly reflects dedication and leadership.Professor Antonio Giordano, M.D., Ph.D., is the creator and head of the Sbarro Health Research Organization, located at Temple University‘s College of Science and Technology in Philadelphia. Stay connected with him through his various social media platforms, including Facebook, LinkedIn, Twitter, and Instagram