Category: Post & News

Antonio: The rapid increase in mental illnesses and the high suicide rate Post & News admin March 25, 2024 According to the World Health Organization (WHO), approximately 700,000 people commit suicide every year. The presence of a mental disorder or fragility is an increasingly widespread condition, especially following the Covid pandemic which has contributed to worsening situations of mental health impairment, never recorded before. The sudden change in mood, sleep disturbances, loss of appetite, isolation are signs that should be talked about in order to prevent the diagnosis of mental illness or potential suicide from arriving too late to avoid the worst.Mental disorder is a “clinically significant” alteration of the cognitive sphere and of the regulation of emotions which reflects on a dysfunction in the processes of mental functioning from a biological, psychological and evolutionary point of view. The causes can be environmental, individual, familial or biological. Each person has significant daily variability in their mood based on circumstances, but the sudden and unjustified change in mood can also be determined by the intake of substances.In any case, it is “indicative” of the emergence of a mental problem that should not be underestimated, as anxiety, social pressure, dissatisfaction and exclusion, together with the depressive state, can lead to episodes of self-harm and, in the most serious cases, suicide. While the world is seeing an increase in suicide cases, the most serious situation is in Lesotho, a mountainous, landlocked African kingdom of around 2.3 million people with around 87.5 suicides per 100,000 people. The reasons are always complicated and include abuse, chronic pain, financial problems, addiction, loneliness, latent mental illness and not brought to light through early diagnosis.It is possible to escape from mental illness, through drugs, treatment and therapy with experts, even if often a devaluation of the emotional state, in the face of perfect physical health, affects the difficulty in arriving at evidence of the seriousness of the problem. The lack of the idea of the future, of a true perspective, are elements on the dramatic rise in our contemporary culture, which favor the dissolution of possible family or friend references.Mental illness is “invisible” and burrows inside, until it manifests itself; this is why we need to increase sensitivity and the culture of prevention and use ever greater funds in what has been defined as the Pandemic within the Pandemic: the exponential increase in suicides and mental illnesses in adults and adolescents. Raising the alarm is necessary to understand which strategies and synergies should be activated.In the picture, Dr. Antonio Giordano stands alongside Rocco Commisso, the owner of ACF Fiorentina, and the beloved Joe Barone, CEO of ACF Fiorentina, capturing a moment of camaraderie and shared dedication to the beautiful game.Professor Antonio Giordano, M.D., Ph.D., is the creator and head of the Sbarro Health Research Organization, located at Temple University‘s College of Science and Technology in Philadelphia. Stay connected with him through his various social media platforms, including Facebook, LinkedIn, Twitter, and Instagram

Mesothelioma Protein Identified With Cancer Inhibiting Effect Post & News admin October 1, 2024 Newswise — The recently discovered protein KLHL14 has been identified to have characteristics that may function as a potential tumor suppressor in mesothelioma.Investigators from the Sbarro Institute for Cancer Research and Molecular Medicine, and the Center for Biotechnology at Temple University, including Dr. Angelo Canciello, Dr. Reyes Benot Dominguez, Dr. Antonio Giordano and Dr. Andrea Morrione, in collaboration with Dr. Barbara Barboni from the University of Teramo, Italy, publish their findings on the protein KLHL14 in the study entitled “Characterization of KLHL14 anti-oncogenic action in malignant mesothelioma,” in the international-peer-reviewed journal Heliyon.In this study, the authors demonstrated that the protein KLHL14 both prevents epithelial-to mesenchymal-transition, which is a mechanism used by cancer cells to become more aggressive, and plays an anti-oncogenic role in mesothelioma. KLHL14 targeting by siRNA resulted in enhanced proliferation, motility, invasion and colony formation in mesothelioma cells, which indicates its role as an inhibitor of cancer progression.“This research is an important step further to decipher KLHL14’s mechanism of action,” says Antonio Giordano, M.D., Ph.D., President and Founder of the Sbarro Health Research Organization (SHRO) at Temple University. “Our findings contribute to the understanding of the molecular mechanisms regulating mesothelioma initiation and progression,” he concludes.“Our study provides the novel observation of a potential mechanism of KLHL14 regulation by a molecule called TGF-Beta,” adds senior author Andrea Morrione, Ph.D., Research Professor at Temple University and Deputy Director of the Sbarro Institute for Cancer Research and Molecular Medicine. “Additional research is needed to understand the KLHL/TGF axis,” explains Morrione, “and to potentially develop KLHL14-based drugs for Mesothelioma and other deadly cancers with few treatment options.”In the picture, Dr. Antonio Giordano stands alongside Rocco Commisso, the owner of ACF Fiorentina, and the beloved Joe Barone, CEO of ACF Fiorentina, capturing a moment of camaraderie and shared dedication to the beautiful game.Professor Antonio Giordano, M.D., Ph.D., is the creator and head of the Sbarro Health Research Organization, located at Temple University‘s College of Science and Technology in Philadelphia. Stay connected with him through his various social media platforms, including Facebook, LinkedIn, Twitter, and Instagram

Remembering Joe Barone: A Tribute to a Remarkable Individual and a good friend Post & News admin October 1, 2024 Today, our hearts are heavy as we come together to mourn the loss of Joe Barone – a dear friend, a visionary leader, and an exceptional individual whose impact reached far beyond the realms of sport. With profound sadness, we bid farewell to a man whose dedication and passion for innovation have left an indelible mark on the world of football and beyond.Joe’s unwavering support for our program of sport genomics exemplified his commitment to pushing the boundaries of possibility. His invitation to collaborate with the medical team of Fiorentina Calcio was not just a gesture of professional courtesy but a testament to his relentless pursuit of excellence and his belief in the power of collaboration to drive meaningful change.In this moment of profound loss, we extend our deepest condolences to the Barone family – to his beloved wife, Camilla, and their cherished children, Pietro, Salvatore, Giuseppe, and Gabriella. Our thoughts and prayers are with you as you navigate this difficult time, finding solace in the memories of a remarkable husband, father, and friend.Joe’s legacy will endure in the hearts of all His unwavering dedication to improving the world of football and beyond will continue to inspire us to reach new heights and strive for excellence in all that we do. As we bid farewell to a dear friend, we take comfort in knowing that his spirit will live on in the countless lives he touched and the lasting impact he leaves behind.Rest in peace, dear Joe. Your presence will be deeply missed, but your legacy will forever shine brightly.In the picture, Dr. Antonio Giordano stands alongside Rocco Commisso, the owner of ACF Fiorentina, and the beloved Joe Barone, CEO of ACF Fiorentina, capturing a moment of camaraderie and shared dedication to the beautiful game.Professor Antonio Giordano, M.D., Ph.D., is the creator and head of the Sbarro Health Research Organization, located at Temple University‘s College of Science and Technology in Philadelphia. Stay connected with him through his various social media platforms, including Facebook, LinkedIn, Twitter, and Instagram

SHRO and Temple Create iNest to Commercialize Innovations Post & News admin October 1, 2024 Newswise — With funding from the Commonwealth of Pennsylvania and the Sbarro Health Research Organization (SHRO), the latest incubator and technology transfer institute opens at Temple University. This new Innovation Nest (iNest) will provide facilities as well as the resources to effetively develop and deploy real-world applications for their research work.This week, the iNest celebrates its grand opening, with honored guests to commemorate this exciting new partnership hub on campus with an open house.“I am proud to see SHRO’s partnership with Temple University manifest tangibly through the groundbreaking of the iNest,” says Antonio Giordano, M.D., Ph.D., Founder and President of SHRO, where he directs the research of faculty and students collaborating with the Sbarro Institute for Cancer Research and Molecular Biology located at the Temple University College of Science and Technology since 2002. “The iNest is a testament to our commitment to fostering innovation and real-world impact within the research community,” adds Giordano.The iNest is over 8,000 square feet in the center of Temple’s innovation ecosystem, connecting and guiding researchers, innovators, entrepreneurs, and startups looking for meaningful partnerships. There they will have access to space and equipment such as wet labs, cell culture rooms, clean rooms, gene sequencing, and high-throughput computing, with event space and dining.The iNest has been made possible with the support of The Office of the Vice President for Research. “In my years of service as a Director and general counsel to SHRO,” says Philadelphia attorney and SHRO Board member Dirk Simpson, “the iNest marks an important milestone on a truly enjoyable journey of collaboration with Temple University.” At the iNest, Temple technology commercializations will seek out new innovations from Temple faculty, offer them resources to develop those innovations, and provide resources to protect their work. It also houses an office for student innovations and other Temple University spinout companies. The iNest will also host educational programs and events to connect the community of educators, students, and local entrepreneurs.The Grand Opening will take place Tuesday, March 19, 2024 from 3:45 PM – 5:30 PM. Learn More Professor Antonio Giordano, M.D., Ph.D., is the creator and head of the Sbarro Health Research Organization, located at Temple University‘s College of Science and Technology in Philadelphia. Stay connected with him through his various social media platforms, including Facebook, LinkedIn, Twitter, and Instagram

IX edition [Faith and Science Vincenzo De Colibus] International Award Post & News admin March 11, 2024 On Tuesday 19 March, in the historic council chamber of the Municipality of Sarno, the prestigious event sponsored by the Municipality of Sarno and organized by the Association of Italian Catholic Commis-medicines of the Campania region, chaired by Professor Mario Ascolese, will take place at 9 am. The award is dedicated to Doctor Vincenzo De Colibus, beloved president of the Amci section of the Nocera-Sarno diocese and tireless man of faith and science, pioneer of endoscopic gastroenterology. He holds the distinction of having created the digestive endoscopy service at Villa Malta hospital in Sarno. The Faith and Science Vincenzo De Colibus award depicts Pegasus because it represents the strength of science that hovers on the wings of faith. This prestigious award will be awarded to Professor Antonio Giordano, director of the Sbarro Institute for Cancer Research and Molecular Medicine and Center for Biotechnology in the College of Science and Technology of Temple University in Philadelphia. Instead, the young Maria Cuomo, a PhD student of molecular biology in Medical Biotechnology at University of Siena, will obtain the scholarship offered by the Association of Italian Catholic Doctors in the Campania region. The scholarship is dedicated to young researchers deserving for their studies and research: in fact, Cuomo currently works at the Sbarro health research organization at Temple University in Philadelphia and is present in Professor Giordano’s research group. For the occasion, Maria Cuomo will connect via video call from Philadelphia to offer her greetings to those present.The main theme of the event is environmental pollution in the land of fires and at the same time the onset of tumors in the subjects who live there. Professor Giordano, author of 700 scientific publication, talks about it with his lectio magistralis Geni, environment and cancer: in the land of fires and poisons.” Recent studies carried out by the group of Professor Giordano of the Sbarro Institute, in which Maria Cuomo is also present, in collaboration with the National Cancer Institute of Naples Pascale Foundation, coordinated by Professor Luigi Alfano, have demonstrated that in people suffering from cancer the expression Cdk9 is altered, therefore its absence guarantees greater sensitivity to cancerous cells to chemotherapy treatments, thus adding an important new element in the fight against cancer.The recognition by the entire international community towards Professor Giordano for the high professionalism of his work declares Ascolese – is a sincere attestation of esteem and respect for a professional who puts his work at the service of the faith, strongly supporting and clarity of one’s convictions as a scientist and believer.” The lectio magistralis will be preceded by the greetings of Professor Mario Ascolese, by the institutional greetings of the lawyer Eutilia Viscardi, acting mayor of the Municipality of Sarno, who actively collaborated for the realization of the event, then followed by the institutional greetings of Professor Annamaria Della Porta , councilor with responsibility for events and shows of the Municipality of Sarno, and finally the journalist Salvatore Campitiello, president of Assostampa Valle del Sarno, councilor and treasurer of the order of journalists of Campania, will offer his greetings.The event will be moderated by the Viridiana journalist Myriam Salerno, press officer of the Association of Italian Catholic Doctors of the Campania region. The patronage linked to the award is prestigious, the Shro is located within the Temple University of Philadelphia, it belongs to this university for research to combat cancer, the Order of Doctors and Dentists of Salerno, the Italian Society of Environmental Medicine directed by Professor Alessandro Miani, the Euro-Mediterranean Biomedical Scientific Institute directed by Professor Alessandro Dtante who has trained many researchers, the UniSi of Siena, the UniSa of Salerno, the Accademia Tiberina Lucana section directed by Professor Nicola Pascale, the Salerno medical school studies directed by Professor Giovanni Canora, the Pro Loco of Sarno and, for the occasion, the president Vincenzo Cerrato, will deliver 2 plaques to the scholarship holder and the prize winner respectively. Thanks to the sponsors: TinSider, the FD Designer who has always been close to the promotion of cultural events. The well-known pastry shop Pepe master confectioner will delight the palates of those present with its characteristic zeppole of San Giuseppe, as March 19th is the day dedicated to the father of Jesus.Professor Antonio Giordano, M.D., Ph.D., is the creator and head of the Sbarro Health Research Organization, located at Temple University‘s College of Science and Technology in Philadelphia. Stay connected with him through his various social media platforms, including Facebook, LinkedIn, Twitter, and Instagram