Childhood Cancers
Definition
Childhood cancers are a group of cancers that occur in infants, children, adolescents, and young adults. They differ significantly from adult cancers in terms of types, causes, and treatment approaches.
Characteristics
The most common types include leukemia, brain and central nervous system tumors, neuroblastoma, Wilms tumor, lymphoma, and bone cancers like osteosarcoma and Ewing sarcoma. Unlike many adult cancers, childhood cancers are not typically linked to lifestyle or environmental risk factors.
Diagnosis and Prognosis
Diagnosis involves a combination of physical exams, imaging (MRI, CT, X-rays), blood tests, and biopsies. Prognosis varies by cancer type, stage, and response to treatment. Survival rates for many childhood cancers have improved significantly thanks to advances in therapies.
Treatment
Treatments may include surgery, chemotherapy, radiation therapy, targeted therapy, or stem cell transplant. Because children are still growing, treatments are carefully adjusted to minimize long-term side effects. Survivorship care is essential to monitor and manage any late effects.
Last Revised: 12 May , 2025
Glossary
- Glioma Astrocytomas
- Childhood Ependymoma
- Diffuse Intrinsic Pontine Glioma
- Atypical Teratoid/Rhabdoid Tumor
- Childhood Medulloblastoma
- Childhood Craniopharyngioma
- Kaposi Sarcoma
- Childhood Soft Tissue Sarcoma
- Uterine Sarcoma
- Small Intestine Cancer
- Stomach Cancer
- Thymoma and Thymic Carcinoma
- Childhood Thymoma and Thymic Carcinoma
- Thyroid Cancer
- Childhood Thyroid Cancer
- Urethral Cancer
- Vaginal Cancer
- Vulvar Cancer
- Adult Brain Tumors
- Osteosarcoma
- Ovarian Low Malignant Potential Tumors
- Childhood Ovarian Cancer
- Pheochromocytoma and Paraganglioma
- Childhood Pheochromocytoma
- Parathyroid Cancer
- Penil Cancer
- Pituitary Tumors
- Multiple Myeloma
- Breast Cancer Pregnancy
- Prostate Cancer
- Recurrent Cancer
- Intraocular Melanoma
- Retinoblastoma
- Skin Cancer
- Childhood Skin Cancer
- Melanoma
- Childhood Melanoma
- Merkel Cell Carcinoma
- Neuroblastoma
- Non-Small Cell Lung Cancer (NSCLC)
- Small Cell Lung Cancer (SCLC)
- Pleuropulmonary Blastoma (PPB)
- Childhood Tracheobronchial Tumors
- Langerhans Cell Histiocytosis (LCH)
- Esthesioneuroblastoma
- Childhood Acute Lymphoblastic Leukemia (ALL)
- Childhood Acute Myeloid Leukemia (AML)
- Liver Cancer
- Childhood Liver Cancer
- Hodgkin Lymphoma
- Mycosis Fungoides
- Childhood Hodgkin Lymphoma
- Childhood Non-Hodgkin Lymphoma (NHL)
- Male Breast Cancer
- Childhood Breast Cancer
- Oropharyngeal Cancer
- Paranasal Sinus and Nasal Cavity Cancer
- Salivary Gland Cancer
- Soft Tissue Sarcoma
- Rhabdomyosarcoma
- Childhood Vascular Tumors
- Intraocular Melanoma
- Pancreatic Cancer
- Pancreatic Neuroendocrine Tumors
- Childhood Pancreatic Cancer
- Kidney Cancer
- Transitional Cell Cancer of the Renal Pelvis and Ureter
- Wilms Tumor
- Germ Cell Tumors Childhood CNS
- Germ Cell Tumors Childhood Extracranial
- Germ Cell Tumors Extragonadal
- Germ Cell Tumor Ovarian
- Testicular Cancer
- Gestational Trophoblastic Disease (GTD)
- Hairy Cell Leukemia
- Hypopharyngeal Cancer
- Laryngeal Cancer
- Lip and Oral Cavity Cancer
- Metastatic Squamous Neck Cancer
- Nasopharyngeal Cancer
- Diffuse Intrinsic Pontine Glioma (DIPG)
- Embryonal Tumors Childhood CNS
- Endometrial Cancer
- Ependymoma Childhood
- Esophageal Cancer
- Ewing Sarcoma
- Extracranial Germ Cell Tumors
- Extragonadal Germ Cell Tumors
- Fallopian Tube Cancer
- Gallbladder Cancer
- Gastric Stomach Cancer
- Gastrointestinal Neuroendocrine Tumors
- Gastrointestinal Stromal Tumor
- Burkitt Lymphoma
- Carcinoma of Unknown Primary
- Cervical Cancer
- Childhood Cancers
- Childhood Cardiac Tumors
- Childhood Cancers Rare
- Cholangiocarcinoma
- Chordoma ChildhoodÂ
- Chronic Lymphocytic Leukemia (CLL)
- Chronic Myeloid Leukemia (CML)
- Colon Cancer
- Craniopharyngioma Childhood
- Ductal Carcinoma
- AIDS-Related Lymphoma
- Anal Cancer
- Appendix Cancer
- Astrocytoma
- Atypical Teratoid
- Basal Cell Carcinoma (BCC)
- Bile Duct Cancer
- Bladder Cancer
- Bone Cancer
- Brain Tumors
- Breast Cancer
- Bronchial Tumors (Lung cancer)
- Acute Lymphoblastic Leukemia (ALL)
- Acute Myeloid Leukemia (AML)
- Adrenocortical Carcinoma