Gastric Stomach Cancer

Definition

Stomach cancer, also known as gastric cancer, begins in the lining of the stomach. Most cases are adenocarcinomas, arising from the glandular cells that produce stomach mucus and fluids.

Characteristics

Early stomach cancer often causes no symptoms. As it progresses, symptoms may include indigestion, stomach pain, nausea, weight loss, loss of appetite, and difficulty swallowing. Risk factors include infection with Helicobacter pylori, smoking, a diet high in smoked or salted foods, and certain genetic conditions.

Diagnosis and Prognosis

Diagnosis involves endoscopy with biopsy, imaging tests like CT scans, and sometimes exploratory surgery. Prognosis depends on the stage at diagnosis. Early detection offers the best chance for successful treatment, but many cases are found at advanced stages.

Treatment

Treatment options include surgery, chemotherapy, radiation therapy, targeted therapy, and immunotherapy. The approach depends on the cancer’s stage, location, and molecular features.

Last Revised: 12 May , 2025