Chordoma Childhood 

Definition

Chordoma is a rare, slow-growing bone cancer that arises from remnants of the notochord, a structure present during fetal development. In children, it typically forms at the base of the skull or in the spine.

Characteristics

Although it grows slowly, chordoma can be locally aggressive and difficult to treat due to its proximity to critical structures. Symptoms vary depending on location and may include pain, neurological issues, or changes in bladder or bowel function.

Diagnosis and Prognosis

Diagnosis involves MRI, CT scans, and biopsy. Genetic testing may also be used. Chordoma is challenging to cure, especially in children, due to its high recurrence rate and location, but long-term survival is possible with early and complete surgical removal.

Treatment

Treatment typically includes surgery, often followed by high-dose radiation therapy. Complete surgical resection offers the best chance for long-term control. Recurrences are common, and follow-up care is essential.

Last Revised: 12 May , 2025