Hodgkin Lymphoma

Definition

Hodgkin lymphoma is a cancer of the lymphatic system, characterized by the presence of Reed-Sternberg cells, a specific type of abnormal lymphocyte. It typically starts in the lymph nodes but can spread to other parts of the body.

Characteristics

Common symptoms include painless swelling of lymph nodes, fever, night sweats, weight loss, fatigue, and persistent coughing or breathing difficulty if the disease affects the chest. Hodgkin lymphoma often follows a predictable pattern of spread.

Diagnosis and Prognosis

Diagnosis involves lymph node biopsy, imaging tests like CT and PET scans, and blood tests. Prognosis is generally excellent, especially for early-stage disease, with high cure rates using modern therapies.

Treatment

Treatment usually includes chemotherapy, radiation therapy, or a combination of both. In cases of relapse or resistance, stem cell transplantation and targeted therapies may be considered.

Last Revised: 12 May , 2025