Recurrent Cancer

Definition

Recurrent cancer is cancer that returns after treatment and a period of improvement. It can come back in the same place as the original tumor (local recurrence), near the original site (regional recurrence), or in a different part of the body (distant or metastatic recurrence).

Characteristics

The recurrence may happen weeks, months, or even years after initial treatment. Symptoms depend on the cancer type and where it recurs. Some patients may have no symptoms and discover recurrence during routine follow-up scans or blood tests.

Diagnosis and Prognosis

Diagnosis involves imaging tests (CT, MRI, PET scans), biopsies, and blood work to confirm the return of cancer. Prognosis depends on the cancer type, time since initial diagnosis, location of the recurrence, and response to prior treatments.

Treatment

Treatment options vary and may include surgery, chemotherapy, radiation therapy, targeted therapy, immunotherapy, or participation in clinical trials. The approach depends on previous treatments received and current disease characteristics. Palliative care may also be offered to improve quality of life.

Last Revised: 12 May , 2025