Soft Tissue Sarcoma

Definition

Soft tissue sarcoma is a group of rare cancers that develop in the soft tissues of the body, including muscles, fat, blood vessels, nerves, and tendons. It can occur anywhere but is most often found in the arms, legs, chest, or abdomen.

Characteristics

There are many subtypes, such as liposarcoma, leiomyosarcoma, and angiosarcoma. Symptoms typically include a painless lump that grows over time, swelling, or pain if the tumor presses on nerves or muscles.

Diagnosis and Prognosis

Diagnosis involves imaging tests like MRI or CT scans, biopsy, and sometimes molecular testing to determine the sarcoma subtype. Prognosis depends on the tumor’s size, location, grade, and whether it has spread. Early-stage sarcomas have better outcomes.

Treatment

Treatment usually involves surgery to remove the tumor, often combined with radiation therapy. Chemotherapy or targeted therapy may be used for high-grade or advanced sarcomas. Long-term follow-up is important to monitor for recurrence.

Last Revised: 12 May , 2025